Clinical Evidence

Our mission at Affix Medical is grounded in rigorous clinical research. Explore our published literature and white papers detailing the need for improved drainage catheter securement.

Peer-Reviewed Publications

Published

Adverse Events of Surgical Drain Placement: An Analysis of the NSQIP Database

Abhinav Talwar, Ashir Bansal, Gabriel Knight, Juan-Carlos Caicedo, Ahsun Riaz, Riad Salem

TLDR: Using national surgical outcomes data, we found that drains—while often necessary—can be associated with higher infection rates and longer hospital stays. These findings highlight the need for safer, more reliable drain technologies.
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Published

Adverse Events After Percutaneous Transhepatic Biliary Drainage: A 10-Year Retrospective Analysis

Matthew Antalek, Muhammed E Patel, Gabriel M Knight, Asad Malik, Ali Husnain, Kristine Stiff, Abhinav Talwar, Allison Reiland, Albert A Nemcek Jr, Riad Salem, Ahsun Riaz

TLDR: In more than 2,300 biliary drainage procedures, complications were frequent—most commonly bile leaks, catheter occlusion, and drain dislodgement. Improving how drains are stabilized and managed could meaningfully reduce these adverse events.
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Published

Assessing Quality-of-Life and Usability Associated With Percutaneous Drainage Catheters

Anna Lytchakov, Rohan Bhargava, Gabriel M. Knight, Abhinav Talwar, Ahsun Riaz, Riad Salem

TLDR: This study assesses patient-reported quality of life (QoL) and drain usability, finding that percutaneous drains negatively impact QoL and have sub-optimal usability. The findings highlight the critical need for improved drain fixation strategies and optimized patient education.
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White Papers & Clinical Studies

White Paper

Clinical Evaluation of the Affix Clip™: A Prospective Human Usability Study

Gabriel Knight, MD; Abhinav Talwar, MD MBA; Ahsun Riaz, MD; Samdeep Mouli, MD; Riad Salem, MD MBA

TLDR: A prospective pilot usability study conducted at Northwestern Memorial Hospital evaluating the device using the System Usability Scale (SUS). The Affix Clip™ achieved a SUS score of 94.2 (vs. 68.1 for standard of care) with zero catheter dislodgements and high patient satisfaction.
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